AI SearchThe prevention and treatment of missing data in clinical trials / (Record no. 107215)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03251cam a2200289 a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120511s2010 dcua b 000 0 eng c |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780309158145 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0309158141 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | SDU |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R853 |
| Item number | N277 P 2010 |
| 110 2# - CORPORATE NAME | |
| Corporate name | National Research Council (U.S.). |
| 245 14 - TITLE STATEMENT | |
| Title | The prevention and treatment of missing data in clinical trials / |
| Statement of responsibility, etc. | Panel on Handling Missing Data in Clinical Trials, Committee on National Statistics, Division of Behavioral and Social Sciences, National Research Council of the National Academies. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Washington, D.C. : |
| Name of publisher, distributor, etc. | National Academies Press, |
| Date of publication, distribution, etc. | 2010. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 144 p. : |
| Other physical details | ill. |
| 505 0# - Formatted Contents Note | |
| Formatted contents note | Introduction and background -- Trial designs to reduce the frequency of missing data -- Trial strategies to reduce the frequency of missing data -- Drawing inferences from incomplete data -- Principles and methods of sensitivity analyses -- Conclusions and recommendations. |
| 505 0# - Formatted Contents Note | |
| Formatted contents note | HKBU library |
| 518 ## - DATE/TIME AND PLACE OF AN EVENT NOTE | |
| DATE/TIME AND PLACE OF AN EVENT NOTE | YT2025 M09 |
| 520 ## - SUMMARY | |
| Summary | "Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participants discontinue study treatment. Existing guidelines for the design and conduct of clinical trials, and the analysis of the resulting data, provide only limited advice on how to handle missing data. Thus, approaches to the analysis of data with an appreciable amount of missing values tend to be ad hoc and variable. The Prevention and Treatment of Missing Data in Clinical Trials concludes that a more principled approach to design and analysis in the presence of missing data is both needed and possible. Such an approach needs to focus on two critical elements: (1) careful design and conduct to limit the amount and impact of missing data and (2) analysis that makes full use of information on all randomized participants and is based on careful attention to the assumptions about the nature of the missing data underlying estimates of treatment effects. In addition to the highest priority recommendations, the book offers more detailed recommendations on the conduct of clinical trials and techniques for analysis of trial data."--Publisher's description. |
| 650 #0 - SUBJECT | |
| Topical term | Clinical trials |
| General subdivision | Statistical methods. |
| 650 #0 - SUBJECT | |
| Topical term | Experimental design. |
| 650 12 - SUBJECT | |
| Topical term | Randomized Controlled Trials as Topic |
| General subdivision | statistics & numerical data. |
| 650 22 - SUBJECT | |
| Topical term | Biomedical Research |
| General subdivision | standards. |
| 710 2# - CORPORATE NAME | |
| Corporate name | National Research Council (U.S.). |
| Subordinate unit | Committee on National Statistics. |
| 710 2# - CORPORATE NAME | |
| Corporate name | National Academies Press (U.S.) |
| 900 ## - Accession Number | |
| Accession Number | 33314 = C.1 ศูนย์วิทยาศาสตร์ |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | English Books |
| Source of classification or shelving scheme | Library of Congress Classification |
| 650 #0 - SUBJECT | |
| -- | 194133 |
| 650 12 - SUBJECT | |
| -- | 204602 |
| 650 22 - SUBJECT | |
| -- | 204603 |
| 710 2# - CORPORATE NAME | |
| -- | 187834 |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | Available for Loans | General Books | ศูนย์วิทยาศาสตร์ | ศูนย์วิทยาศาสตร์ | General Collection | 23/09/2025 | Donation | R853 N277 P 2010 | 1000364873 | 23/09/2025 | C.1 | 23/09/2025 | English Books |