03804cam a22002774a 4500008004100000020001800041020001500059040000800074050002200082100002300104245013300127260004700260300002000307505133500327505153301662505001703195518001503212650003103227650002303258700002103281700002003302900001403322942001303336999001903349952015803368080410s2008    njua     b    001 0 eng    a9789812706638  a9812706631  aSDU00aR853bC545 U 20081 aChow, Pierce K. H.10aUsing animal models in biomedical research :ba primer for the investigator /cPierce K.H. Chow, Robert T.H. Ng, Bryan E. Ogden.  aHackensack, NJ :bWorld Scientific,c2008.  a290 p. :bill. 0 a1. Scientific considerations and choice of species. The rationale for the use of animal models in biomedical research / Pierce Chow. Experimental animal models in biomedical resarch / Robert Ng. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- 2. Regulatory considerations in the use of animal models. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. The functions of the institutional animal care and use committee / Pierce Chow. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. The 3r's, research variables and the use of alternatives / Hock Soo Ong. Use of statistics as determinant for number of animals used / Huihua Li. The advantages of accreditation with AAALAC / Bryan Ogden -- 3. Animal handling and surgical procedures. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. Blood collection from laboratory animals / Jason Villano. Antibiotic coverage and therapy / Darvi Sergio. Animal preparation and transport / Robert Ng. Preparation and implementation of animal surgery / Robert Ng. Animal intubation / Robert Ng. Anaesthesia and maintenance of homeostasis / Robert Ng. animal euthanasia / Darvi Sergio. Rodent sentinel programme / Peik Khin Tan --0 a4. Basic animal investigative methods. Bioimaging in animals / David Ng ... [et al.]. Histology sampling and techniques / In Chin Song. Animal tissue perfusion and preservation / Robert Ng. Animal cell culture / Peggy Yong and Kai Zhang. Application of microsurgical techniques in animal research / Bien Keem Tan ... [et al.] -- 5. Animal welfare considerations. Species specific caging configuration and design / Cindy Phua. Postoperative care and pain management / Jason Villano. animal feeds and nutritional requirements / Peik Khin Tan -- 6. Safety management of an animal facility. Occupational health and safety programme / Angela Goh. New employee and external users orientation / Inria Kurniawan Then. Radiation safety awareness in animal research / S. Somanesan. Emergency crisis management / Irene Kee. Zoonoses and laboratory animal allergies / Jason Villano -- 7. Supporting facilities design. clinical skills laboratory / Robert Ng. Animal research supporting laboratories / Robert Ng. animal research and housing facilities / Robert Ng -- 8. The development of comprehensive animal facilities in Singapore. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng -- Append. 1. Accredited laboratories for import of experimental animals -- Append. 2. Radiation safety data -- Append. 3. Anaesthesia for laboratory animals -- Append. 4. Analgesics and therapeutics for laboratory animals -- Append. 5. Passively transmitted zoonotic organisms.0 aHKBU library  aYT2025 M08 0aAnimal models in research. 0aMedicinexResearch1 aNg, Robert T. H.1 aOgden, Bryan E.  a= C.1 SDU  cGBE2lcc  c104198d104198  00102lcc406R0853 C545 U2008708CGB9279475aSDUbSDUcGEN3d2025-08-27e2l0oR853 C545 U 2008p1000365655r2025-08-27 00:00:00tC.1w2025-08-27yGBE