02300cam a22002897i 4500 130417s2013 enka b 001 0 eng d 9780230368279 0230368271 9780230202108 SDU QH588 F151 P 2013 Fagan, Melinda Bonnie, 194206 Philosophy of stem cell biology : knowledge in flesh and blood / Melinda Bonnie Fagan, Rice University, USA. Houndmills, Basingstoke, Hampshire : Palgrave Macmillan, 2013 274 p. : ill. New directions in the philosophy of science Visceral Phenomena -- Stem Cell Concepts -- Don't Know What You've Got 'Til It's Gone: Evidence in Stem Cell Experiments -- A State of Uncertainty: Stemness and the Roles of Theory -- Mechanistic Explanation: The Joint Account -- Genes and Development: The Stem Cell Perspective -- Pluripotent Model Organisms -- Social Experiments -- Integrating Stem Cell and Systems Biology -- Clinical Values. HKBU library YT2025 M08 Examining stem cell biology from a philosophy of science perspective, this book clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. The first chapters discuss what stem cells are, how experiments identify them, and why these two issues cannot be completely separated. The basic concepts, methods and structure of the field are set out, as well as key limitations and challenges. The second part of the book shows how rigorous explanations emerge from stem cell experiments, and compares these to other kinds of scientific explanation. Model organisms, the role of genes, and the significance of collaboration are also discussed. The last part of the book considers relations to systems biology and clinical medicine, arguing that both the mathematical models of the former, and ethical principles of the latter, are necessary for stem cell biology to deliver on its promises -- Stem cells Research Philosophy. 194207 Stem cells Research Moral and ethical aspects. 181077 Systems biology. 159494 Clinical medicine. = C.1 SDU GBE lcc 104274 104274 0 0 lcc 0 QH0588 F151 P2013 0 CGB 278355 SDU SDU GEN3 2025-08-19 2 0 QH588 F151 P 2013 1000365264 2025-08-19 00:00:00 C.1 2025-08-19 GBE