02472cam a22003017i 4500008004100000020001800041020001500059020001800074040000800092050002300100100003500123245011500158260007000273300001900343490004800362505040100410505001700811518001500828520096200843650004601805650006101851650002901912650002301941900001401964942001301978999001901991952016002010130417s2013    enka     b    001 0 eng d  a9780230368279  a0230368271  a9780230202108  aSDU00aQH588bF151 P 20131 aFagan, Melinda Bonnie,919420610aPhilosophy of stem cell biology :bknowledge in flesh and blood /cMelinda Bonnie Fagan, Rice University, USA.  a Houndmills, Basingstoke, Hampshire : bPalgrave Macmillan,c2013  a274 p. :bill.  aNew directions in the philosophy of science0 aVisceral Phenomena -- Stem Cell Concepts -- Don't Know What You've Got 'Til It's Gone: Evidence in Stem Cell Experiments -- A State of Uncertainty: Stemness and the Roles of Theory -- Mechanistic Explanation: The Joint Account -- Genes and Development: The Stem Cell Perspective -- Pluripotent Model Organisms -- Social Experiments -- Integrating Stem Cell and Systems Biology -- Clinical Values.0 aHKBU library  aYT2025 M08  aExamining stem cell biology from a philosophy of science perspective, this book clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. The first chapters discuss what stem cells are, how experiments identify them, and why these two issues cannot be completely separated. The basic concepts, methods and structure of the field are set out, as well as key limitations and challenges. The second part of the book shows how rigorous explanations emerge from stem cell experiments, and compares these to other kinds of scientific explanation. Model organisms, the role of genes, and the significance of collaboration are also discussed. The last part of the book considers relations to systems biology and clinical medicine, arguing that both the mathematical models of the former, and ethical principles of the latter, are necessary for stem cell biology to deliver on its promises -- 0aStem cellsxResearchxPhilosophy.9194207 0aStem cellsxResearchxMoral and ethical aspects.9181077 0aSystems biology.9159494 0aClinical medicine.  a= C.1 SDU  cGBE2lcc  c104274d104274  00102lcc406QH0588 F151 P2013708CGB9278355aSDUbSDUcGEN3d2025-08-19e2l0oQH588 F151 P 2013p1000365264r2025-08-19 00:00:00tC.1w2025-08-19yGBE