02781cam a2200301 a 4500 110927s2012 njua b 001 0 eng 9780470170830 0470170832 SDU R853 P74 2012 Predictive approaches in drug discovery and development : biomarkers and in vitro/in vivo correlations / edited by J. Andrew Williams ... [et al.]. Hoboken, N.J. : Wiley, 2012 . 387 p. : ill. Wiley series on technologies for the pharmaceutical industry The importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin. HKBU library YT2025 M08 Biochemical markers. 205789 Drug development. Pharmaceutical technology. 159324 Biomarkers, Pharmacological. 159489 Drug Discovery. 159491 Drug Evaluation, Preclinical. 205790 Technology, Pharmaceutical. 193904 Williams, J. Andrew. 205791 32508 = C.1 ศูนย์วิทยาศาสตร์ GBE lcc 107625 107625 0 0 lcc 0 R0853 P74 02012 0 CGB 278788 SC SC GEN 2025-08-21 2 R853 P74 2012 1000385879 2025-08-21 00:00:00 C.1 2025-08-21 GBE