biomarkers and in vitro/in vivo correlations Williams, J. Andrew. text bibliography nju Hoboken, N.J Wiley 2012 monographic eng

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387 p. : ill. The importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin. HKBU library edited by J. Andrew Williams ... [et al.]. YT2025 M08 Biochemical markers Drug development Pharmaceutical technology Biomarkers, Pharmacological Drug Discovery Drug Evaluation, Preclinical Technology, Pharmaceutical R853 P74 2012 9780470170830 0470170832 SDU 110927