02942cam a2200313 a 4500008004100000020001800041020001500059040000800074050001900082245015400101260003600255300001900291490006500310505169700375505001702072518001502089650003302104650002202137650003902159650004102198650002802239650004202267650004002309700003302349900006502382942001302447999001902460952014902479110927s2012    njua     b    001 0 eng    a9780470170830  a0470170832  aSDU00aR853bP74 201200aPredictive approaches in drug discovery and development :bbiomarkers and in vitro/in vivo correlations /cedited by J. Andrew Williams ... [et al.].  aHoboken, N.J. :bWiley,c2012 .  a387 p. :bill.1 aWiley series on technologies for the pharmaceutical industry0 aThe importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin.0 aHKBU library  aYT2025 M08 0aBiochemical markers.9205789 0aDrug development. 0aPharmaceutical technology.915932412aBiomarkers, Pharmacological.915948912aDrug Discovery.915949122aDrug Evaluation, Preclinical.920579022aTechnology, Pharmaceutical.91939041 aWilliams, J. Andrew.9205791  a32508 = C.1 ศูนย์วิทยาศาสตร์  cGBE2lcc  c107625d107625  00102lcc406R0853 P74  02012708CGB9278788aSCbSCcGENd2025-08-21e2oR853 P74 2012p1000385879r2025-08-21 00:00:00tC.1w2025-08-21yGBE