000			02781cam a2200301 a 4500
008			110927s2012 njua b 001 0 eng
020			_a9780470170830
020			_a0470170832
040			_aSDU
050	0	0	_aR853 _bP74 2012
245	0	0	_aPredictive approaches in drug discovery and development : _bbiomarkers and in vitro/in vivo correlations / _cedited by J. Andrew Williams ... [et al.].
260			_aHoboken, N.J. : _bWiley, _c2012 .
300			_a387 p. : _bill.
490	1		_aWiley series on technologies for the pharmaceutical industry
505	0		_aThe importance of biomarkers in translational medicine / Joseph Fleishaker -- Fit for purpose validation of biochemical assays : challenges and solutions / Gabriella Szekely-Klepser and Scott Fountain -- Transcriptional profiling in biomarker discovery / Michael E. Burczynski ... [et al.] -- Proteomic biomarker approaches in drug discovery and development / Ruth A. Vanbogelen, Jeffrey D. Thomas, and Diane Alessi -- Application of metabolomics to pharmaceutical research and development / Qiuwei Xu and William H. Schaefer -- Vascular biomarkers and imaging studies / Karin Potthoff, Ulrike Fiedler, and Joachim Drevs -- Cardiovascular biomarkers as examples of success and failure in predicting safety in humans / Simon Authier ... [et al.] -- Use of molecular imaging for receptor occupancy decision making in drug development / R. Paul Maguire -- Biosensors for clinical biomarkers / Sara Tombelli and Marco Mascini -- US regulatory perspective on biomarker development / Rajnikath Madabushi, Lawrence Lesko, and Janet Woodcock -- EU regulatory perspective on biomarkers / Ian Hudson -- Use of biomarkers in drug development : Japanese perspectives / Yoshiaki Uyama ... [et al.] -- In vitro-in vivo correlations of hepatic drug clearance / R. Scott Obach -- The potential of in silico and in vitro approaches to predict in vivo drug-drug interactions and ADMET/TOX properties / Kenneth Bachmann and Sean Ekins -- In vitro-in vivo correlations in drug discovery and development : concepts and applications in toxicology / Rex Denton, Kimberly Brannen, and Buce D. Car -- Assessing the potential for induction of cytochrome P450 enzymes and predicting the in vivo response / Jiunn H. Lin.
505	0		_aHKBU library
518			_aYT2025 M08
650		0	_aBiochemical markers. _9205789
650		0	_aDrug development.
650		0	_aPharmaceutical technology. _9159324
650	1	2	_aBiomarkers, Pharmacological. _9159489
650	1	2	_aDrug Discovery. _9159491
650	2	2	_aDrug Evaluation, Preclinical. _9205790
650	2	2	_aTechnology, Pharmaceutical. _9193904
700	1		_aWilliams, J. Andrew. _9205791
900			_a32508 = C.1 ศูนย์วิทยาศาสตร์
942			_cGBE _2lcc
999			_c107625 _d107625